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01-04-2000 | Artikelen

De rol van micro-organismen bij de ontwikkeling van allergie, inzichten en mogelijkheden van preventie

Auteur: H. J. Neijens

Gepubliceerd in: Tijdschrift voor Kindergeneeskunde | Uitgave 2/2000

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Samenvatting

Micro-organismen, met name virussen, kunnen op diverse wijze een rol spelen bij het verloop van allergische aandoeningen. Een aantal epidemiologische waarnemingen suggereert dat een relatief hoge frequentie van respiratoire infecties samengaat met een relatief lage prevalentie van allergie en astma. Leefomstandigheden die samengaan met relatief veel luchtweginfecties (grote gezinnen, meerdere oudere kinderen, vroeg crèchebezoek) zijn geassocieerd met minder voorkomen van astma. Hierop is het concept gebaseerd dat infecties beschermend kunnen werken tegen allergische aandoeningen. Daarentegen blijkt dat respiratoire infecties een veel voorkomende ( 80%) trigger vormen van astmatische exacerbaties, met name bij jonge kinderen, hetgeen gepaard gaat met de inductie van bronchiale hyperreactiviteit en ontstekingsfenomenen.
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Metagegevens
Titel
De rol van micro-organismen bij de ontwikkeling van allergie, inzichten en mogelijkheden van preventie
Auteur
H. J. Neijens
Publicatiedatum
01-04-2000
Uitgeverij
Bohn Stafleu van Loghum
Gepubliceerd in
Tijdschrift voor Kindergeneeskunde / Uitgave 2/2000
Print ISSN: 0376-7442
Elektronisch ISSN: 1875-6840
DOI
https://doi.org/10.1007/BF03061304