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Journal of Autism and Developmental Disorders

Gepubliceerd in:

29-08-2023 | Original Paper

Examining Phenotypical Heterogeneity and its Underlying Factors in Gesture Skills of Chinese Autistic Children: Clustering Analysis

Auteurs: Xin Zhang, Xue-Ke Song, Wing-Chee So

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 9/2024

Abstract

Purpose: The heterogeneity of autism is well documented, but few studies have studied the heterogeneity of gesture production ability in autistic children. The present study aimed to identify subgroups of autistic children who displayed heterogeneous gesture production abilities and explore the underlying factors, including autism characteristics, intellectual ability, and language ability, that were associated with the heterogeneity. Methods: A total of 65 Chinese autistic children (mean age = 5;3) participated. Their autism characteristics and intellectual ability were assessed by standardized measurements. Language output and gesture production were captured from a parent-child interaction task. Results: We conducted a hierarchical cluster analysis and identified four distinct clusters. Cluster 1 and Cluster 2 both had low gesture production whereas Cluster 3 and Cluster 4 had high gesture production. Both Clusters 1 and 2 had relatively strong autism characteristics, in comparison to Clusters 3 and 4. Conclusions: Our findings revealed that children with stronger autism characteristics may gesture less often than those with weaker characteristics. However, the relationship between language ability and intellectual ability and gesture production was not clear. These findings shed light on the directions of intervention on gesture production for autistic children, especially those with stronger autism characteristics.

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The present study also conducted a preliminary analysis to investigate whether parental inputs were associated with gesture production in children in different clusters. Our results did not reveal any differences between any pairs of clusters (see Appendix 2 for a detailed description of analyses).

American Psychiatric Association, D. S. (2013). Diagnostic and statistical manual of mental disorders (DSM-5) (5 vol.). American Psychiatric Association.

Braddock, B. A., Gabany, C., Shah, M., Armbrecht, E. S., & Twyman, K. A. (2016). Patterns of gesture use in adolescents with autism spectrum disorder. American Journal of Speech-Language Pathology, 25(3), 408–415. https://doi.org/10/gm9wqn.

Broome, K., McCabe, P., Docking, K., Doble, M., & Carrigg, B. (2021). Speech abilities in a heterogeneous group of children with autism. Journal of Speech, Language, and Hearing Research, 64(12), 4599–4613. https://doi.org/10/gqxkhj.

Broome, K., McCabe, P., Docking, K., Doble, M., & Carrigg, B. (2022). Speech development across subgroups of autistic children: A longitudinal study. Journal of Autism and Developmental Disorders. https://doi.org/10/grmkf3.

Caselli, M. C., Vicari, S., Longobardi, E., Lami, L., Pizzoli, C., & Stella, G. (1998). Gestures and words in early development of children with Down syndrome. Journal of Speech Language and Hearing Research, 41(5), 1125–1135. https://doi.org/10.1044/jslhr.4105.1125.CrossRef

Charman, T., Drew, A., Baird, C., & Baird, G. (2003). Measuring early language development in preschool children with autism spectrum disorder using the MacArthur Communicative Development Inventory (Infant Form). Journal of Child Language, 30(1), 213–236. https://doi.org/10.1017/S0305000902005482.CrossRefPubMed

Chevallier, C., Kohls, G., Troiani, V., Brodkin, E. S., & Schultz, R. T. (2012). The social motivation theory of autism. Trends in Cognitive Sciences, 16(4), 231–239. https://doi.org/10.1016/j.tics.2012.02.007.CrossRefPubMedPubMedCentral

Choi, B., Shah, P., Rowe, M. L., Nelson, C. A., & Tager-Flusberg, H. (2020). Gesture development, caregiver responsiveness, and language and diagnostic outcomes in infants at high and low risk for autism. Journal of Autism and Developmental Disorders, 50(7), 2556–2572. https://doi.org/10/gpmwnm.

de Giacomo, A., & Fombonne, E. (1998). Parental recognition of developmental abnormalities in autism. European child & adolescent psychiatry, 7(3), 131–136.CrossRef

de Marchena, A., & Eigsti, I. M. (2010). Conversational gestures in autism spectrum disorders: Asynchrony but not decreased frequency. Autism Research, 3(6), 311–322. https://doi.org/10/b4hc48.

Dolnicar, S. (2002). A review of unquestioned Standards in using cluster analysis for Data-Driven Market Segmentation. Australia: University of Wollongong.

Ellawadi, A. B., & Weismer, S. E. (2014). Assessing gestures in young children with autism spectrum disorder. Journal of Speech Language and Hearing Research, 57(2), 524–531. https://doi.org/10.1044/2013_JSLHR-L-12-0244.CrossRef

Fenson, L. (2007). MacArthur-Bates communicative development inventories. Paul H. Brookes Publishing Company.

Formann, A. (1984). The latent class analysis: Introduction to theory and application. Germany: Beltz.

Georgiades, S., Szatmari, P., Boyle, M., Hanna, S., Duku, E., Zwaigenbaum, L., Bryson, S., Fombonne, E., Volden, J., Mirenda, P., Smith, I., Roberts, W., Vaillancourt, T., Waddell, C., Bennett, T., & Thompson, A. (2013). Investigating phenotypic heterogeneity in children with autism spectrum disorder: A factor mixture modeling approach. Journal of Child Psychology and Psychiatry, 54(2), 206–215. https://doi.org/10.1111/j.1469-7610.2012.02588.x.CrossRefPubMed

Gillespie, M., James, A. N., Federmeier, K. D., & Watson, D. G. (2014). Verbal working memory predicts co-speech gesture: Evidence from individual differences. Cognition, 132(2), 174–180. https://doi.org/10.1016/j.cognition.2014.03.012.CrossRefPubMedPubMedCentral

Goldin-Meadow, S., Mylander, C., de Villiers, J., Bates, E., & Volterra, V. (1984). Gestural communication in deaf children: The effects and noneffects of parental input on early language development. Monographs of the Society for Research in Child Development, 49(3), 1–151. https://doi.org/10.2307/1165838.CrossRefPubMed

Goldin-Meadow, S., Goodrich, W., Sauer, E., & Iverson, J. (2007). Young children use their hands to tell their mothers what to say. Developmental Science, 10(6), 778–785. https://doi.org/10/dzcss5.

Hu, V. W., & Steinberg, M. E. (2009). Novel clustering of items from the Autism Diagnostic Interview-Revised to define phenotypes within autism spectrum disorders. Autism Research, 2(2), 67–77. https://doi.org/10/csc9q7.

Huang, Y., Wong, M. K., Lam, W. Y., Cheng, C. H., & So, W. C. (2020). Gestures in storytelling by preschool chinese-speaking children with and without autism. Frontiers in Psychology, 11, 2305. https://doi.org/10.3389/fpsyg.2020.573212.CrossRef

Huang, Y., Cheng, C. H., Law, W. W., Wong, T., Leung, O. K., & So, W. C. (2022). Gesture development in chinese-speaking preschool children with autism and the roles of parental input and child-based factors. Journal of Speech Language and Hearing Research, 65(6), 2309–2326. https://doi.org/10.1044/2022_JSLHR-21-00494.CrossRef

Iverson, J. M., & Goldin-Meadow, S. (2005). Gesture paves the way for language development. Psychological science, 16(5), 367–371. https://doi.org/10.1111/j.0956-7976.2005.01542.x.CrossRefPubMed

Kaufman, A. S. (2004). Kaufman Brief Intelligence Test, 2nd ed. (KBIT-2). American Guidance Service.

Kim, S. H., Macari, S., Koller, J., & Chawarska, K. (2016). Examining the phenotypic heterogeneity of early autism spectrum disorder: Subtypes and short-term outcomes. Journal of Child Psychology and Psychiatry, 57(1), 93–102. https://doi.org/10/gg2gmq.

Kjellmer, L., Hedvall, Å., Fernell, E., Gillberg, C., & Norrelgen, F. (2012). Language and communication skills in preschool children with autism spectrum disorders: Contribution of cognition, severity of autism symptoms, and adaptive functioning to the variability. Research in Developmental Disabilities, 33(1), 172–180. https://doi.org/10/csj6pz.

Lacombe, N., Dias, T., & Petitpierre, G. (2022). Can gestures give us access to thought? A systematic literature review on the role of co-thought and co-speech gestures in children with intellectual disabilities. Journal of Nonverbal Behavior, 46(2), 119–136. https://doi.org/10.1007/s10919-022-00396-4.CrossRef

Liszkowski, U., Brown, P., Callaghan, T., Takada, A., & de Vos, C. (2012). A prelinguistic gestural universal of human communication. Cognitive Science, 36(4), 698–713. https://doi.org/10.1111/j.1551-6709.2011.01228.x.CrossRefPubMed

Lombardo, M. V., Lai, M. C., & Baron-Cohen, S. (2019). Big data approaches to decomposing heterogeneity across the autism spectrum. Molecular Psychiatry, 24(10), 1435–1450. https://doi.org/10/gg29cz.

Lord, C., Rutter, M., & Le Couteur, A. (1994). Autism Diagnostic Interview-Revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. Journal of Autism and Developmental Disorders, 24(5), 659–685. https://doi.org/10.1007/BF02172145.CrossRefPubMed

Lord, C., Rutter, M., DiLavore, P., Risi, S., Gotham, K., & Bishop, S. (2012). Autism Diagnostic Observation Schedule, 2nd ed. (ADOS-2). Western Psychological Corporation.

MacWhinney, B. (2000). The CHILDES project: The database (2 vol.). Psychology Press.

Manwaring, S. S., Mead, D. L., Swineford, L., & Thurm, A. (2017). Modelling gesture use and early language development in autism spectrum disorder. International Journal of Language & Communication Disorders, 52(5), 637–651. https://doi.org/10.1111/1460-6984.12308.CrossRef

Manwaring, S. S., Stevens, A. L., Mowdood, A., & Lackey, M. (2018). A scoping review of deictic gesture use in toddlers with or at-risk for autism spectrum disorder. Autism & Developmental Language Impairments, 3, 1–27. https://doi.org/10.1177/2396941517751891.CrossRef

Mastrogiuseppe, M., Capirci, O., Cuva, S., & Venuti, P. (2015). Gestural communication in children with autism spectrum disorders during mother–child interaction. Autism, 19(4), 469–481. https://doi.org/10.1177/1362361314528390.CrossRefPubMed

McNeill, D. (1992). Hand and mind: What gestures reveal about thought. University of Chicago Press.

McNeill, D. (2005). Gesture and thought. University of Chicago Press.

Medeiros, K., & Winsler, A. (2014). Parent–child gesture use during problem solving in autistic spectrum disorder. Journal of Autism and Developmental Disorders, 44(8), 1946–1958. https://doi.org/10.1007/s10803-014-2069-y.CrossRefPubMed

Mishra, A., Ceballos, V., Himmelwright, K., McCabe, S., & Scott, L. (2021). Gesture production in toddlers with autism spectrum disorder. Journal of Autism and Developmental Disorders, 51(5), 1658–1667. https://doi.org/10.1007/s10803-020-04647-5.CrossRefPubMed

Mitchell, S., Brian, J., Zwaigenbaum, L., Roberts, W., Szatmari, P., Smith, I., & Bryson, S. (2006). Early language and communication development of infants later diagnosed with autism spectrum disorder. Journal of Developmental & Behavioral Pediatrics, 27(Supplement 2), S69–S78. https://doi.org/10.1097/00004703-200604002-00004.CrossRef

Morett, L. M., O’Hearn, K., Luna, B., & Ghuman, A. S. (2016). Altered gesture and speech production in ASD detract from in-person communicative quality. Journal of Autism and Developmental Disorders, 46(3), 998–1012. https://doi.org/10/f8d9q8.

Munson, J., Dawson, G., Sterling, L., Beauchaine, T., Zhou, A., Koehler, E., Lord, C., Rogers, S., Sigman, M., Estes, A., & Abbott, R. (2008). Evidence for latent classes of IQ in young children with autism spectrum disorder. American Journal on Mental Retardation, 113(6), 439–452. https://doi.org/10/fwkdzs.

Özçalişkan, Ş., Adamson, L. B., & Dimitrova, N. (2016). Early deictic but not other gestures predict later vocabulary in both typical development and autism. Autism, 20(6), 754–763. https://doi.org/10/f8vw82.

Özer, D., & Göksun, T. (2020). Gesture use and processing: A review on individual differences in cognitive resources. Frontiers in Psychology, 11, 2859. https://doi.org/10.3389/fpsyg.2020.573555.CrossRef

Pickles, A., Anderson, D. K., & Lord, C. (2014). Heterogeneity and plasticity in the development of language: A 17-year follow-up of children referred early for possible autism. Journal of Child Psychology and Psychiatry, 55(12), 1354–1362. https://doi.org/10.1111/jcpp.12269.CrossRefPubMed

Silverman, L. B., Bennetto, L., Campana, E., & Tanenhaus, M. K. (2010). Speech-and-gesture integration in high functioning autism. Cognition, 115(3), 380–393. https://doi.org/10/dz4nj7.

Silverman, L. B., Eigsti, I. M., & Bennetto, L. (2017). I tawt i taw a puddy tat: Gestures in canary row narrations by high-functioning youth with autism spectrum disorder. Autism Research, 10(8), 1353–1363. https://doi.org/10/gbvgrs.

So, W. C. (2020). Robot for autism behavioral intervention. The Chinese University of Hong Kong.

So, W. C., & Song, X. K. (2022). Whose gestures are more predictive of expressive language abilities among Chinese-speaking children with autism? A comparison of caregivers’ and children’s gestures. Journal of Autism and Developmental Disorders. https://doi.org/10/gq86wx.

So, W. C., Wong, M. K., Lui, M., & Yip, V. (2015). The development of co-speech gesture and its semantic integration with speech in 6- to 12-year-old children with autism spectrum disorders. Autism, 19(8), 956–968. https://doi.org/10.1177/1362361314556783.CrossRefPubMed

So, W. C., Wong, M. K. Y., Cabibihan, J. J., Lam, C. K. Y., Chan, R. Y. Y., & Qian, H. H. (2016). Using robot animation to promote gestural skills in children with autism spectrum disorders. Journal of Computer Assisted Learning, 32(6), 632–646. https://doi.org/10.1111/jcal.12159.CrossRef

So, W. C., Wong, M. K., Lam, W. Y., Cheng, C. H., Yang, J. H., Huang, Y., Ng, P., Wong, W. L., Ho, C. L., Yeung, K. L., & Lee, C. C. (2018). Robot-based intervention may reduce delay in the production of intransitive gestures in chinese-speaking preschoolers with autism spectrum disorder. Molecular Autism, 9(1), 34. https://doi.org/10.1186/s13229-018-0217-5.CrossRefPubMedPubMedCentral

Song, X. K., & So, W. C. (2021). The influence of child-based factors and parental inputs on expressive language abilities in children with autism spectrum disorder. Autism, 26(6), 1477–1490. https://doi.org/10.1177/13623613211054597.CrossRefPubMed

Song, X. K., Lee, C., & So, W. C. (2021). Examining phenotypical heterogeneity in language abilities in chinese-speaking children with autism: A naturalistic sampling approach. Journal of Autism and Developmental Disorders. https://doi.org/10.1007/s10803-021-05104-7.CrossRefPubMedPubMedCentral

Talbott, M. R., Young, G. S., Munson, J., Estes, A., Vismara, L. A., & Rogers, S. J. (2020). The developmental sequence and relations between gesture and spoken language in toddlers with autism spectrum disorder. Child Development, 91(3), 743–753. https://doi.org/10.1111/cdev.13203.CrossRefPubMed

Van Rentergem, J. A. A., Deserno, M. K., & Geurts, H. M. (2021). Validation strategies for subtypes in psychiatry: A systematic review of research on autism spectrum disorder. Clinical Psychology Review, 87, 102033.CrossRef

Watson, L. R., Crais, E. R., Baranek, G. T., Dykstra, J. R., & Wilson, K. P. (2013). Communicative gesture use in infants with and without autism: A retrospective home video study. American Journal of Speech-Language Pathology, 22(1), 25–39. https://doi.org/10/gg2hdz.

Wittke, K., Mastergeorge, A. M., Ozonoff, S., Rogers, S. J., & Naigles, L. R. (2017). Grammatical language impairment in autism spectrum disorder: Exploring language phenotypes beyond standardized testing. Frontiers in Psychology, 8, 532. https://doi.org/10.3389/fpsyg.2017.00532.CrossRefPubMedPubMedCentral

Wolfers, T., Floris, D. L., Dinga, R., van Rooij, D., Isakoglou, C., Kia, S. M., Zabihi, M., Llera, A., Chowdanayaka, R., Kumar, V. J., Peng, H., Laidi, C., Batalle, D., Dimitrova, R., Charman, T., Loth, E., Lai, M. C., Jones, E., Baumeister, S., & Beckmann, C. F. (2019). From pattern classification to stratification: Towards conceptualizing the heterogeneity of Autism Spectrum Disorder. Neuroscience & Biobehavioral Reviews, 104, 240–254. https://doi.org/10/gq2wk2.

Wong, M. K. Y., & So, W. C. (2018). Absence of delay in spontaneous use of gestures in spoken narratives among children with Autism Spectrum Disorders. Research in Developmental Disabilities, 72, 128–139. https://doi.org/10/gcwk4p.

Zheng, S., Hume, K. A., Able, H., Bishop, S. L., & Boyd, B. A. (2020). Exploring developmental and behavioral heterogeneity among preschoolers with ASD: A cluster analysis on principal components. Autism Research, 13(5), 796–809. https://doi.org/10.1002/aur.2263.CrossRefPubMed

Titel: Examining Phenotypical Heterogeneity and its Underlying Factors in Gesture Skills of Chinese Autistic Children: Clustering Analysis
Auteurs: Xin Zhang
Xue-Ke Song
Wing-Chee So
Publicatiedatum: 29-08-2023
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 9/2024
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-023-06049-9

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Examining Phenotypical Heterogeneity and its Underlying Factors in Gesture Skills of Chinese Autistic Children: Clustering Analysis

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