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Gepubliceerd in:

01-08-2014

Infectieuze complicaties en antibiotische profylaxe bij transrectale echogeleide prostaatbiopsie

Auteurs: dr. A.L.M. Vlek, drs. A.E.C. Ruiter, dr. P.L.M. Vijverberg, dr. J.A. Kaan

Gepubliceerd in: Tijdschrift voor Urologie | Uitgave 5/2014

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Samenvatting

Doel:

Transrectale echogeleide prostaatbiopsie (TRUS-PB) vindt doorgaans plaats onder ciprofloxacineprofylaxe. In de westerse wereld wordt een stijging gezien in het gebruik van ciprofloxacine en resistentie van gramnegatieve verwekkers. Wij onderzochten of er een toename aantoonbaar is in incidentie van infectieuze complicaties na TRUS-PB, en of er literatuur beschikbaar is die aanpassing van het huidige profylactische regime ondersteunt.

Methoden:

Retrospectieve analyse van klinische en microbiologische gegevens in het St. Antonius Ziekenhuis en literatuuronderzoek naar profylactische regimes.

Resultaten:

Analyse van 2736 ingrepen toonde een stijging aan in de incidentie van koorts na TRUS-PB van 0,4% in 2008 tot 3,0% in 2011. Ook de incidentie van urineweginfecties, sepsis en ciprofloxacineresistentie onder verwekkers nam toe. Er is geen literatuur beschikbaar die de overstap naar een ander profylactisch regime ondersteunt.

Conclusie:

Infectieuze complicaties na TRUS-PB nemen toe. Een urinekweek dient verricht te worden voorafgaand aan antibiotische behandeling. Als profylaxe verdient een eenmalige dosering ciprofloxacine de voorkeur. De verwachte verdere stijging in ciprofloxacineresistentie maakt meer onderzoek naar alternatieve profylaxe noodzakelijk.
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Metagegevens
Titel
Infectieuze complicaties en antibiotische profylaxe bij transrectale echogeleide prostaatbiopsie
Auteurs
dr. A.L.M. Vlek
drs. A.E.C. Ruiter
dr. P.L.M. Vijverberg
dr. J.A. Kaan
Publicatiedatum
01-08-2014
Uitgeverij
Bohn Stafleu van Loghum
Gepubliceerd in
Tijdschrift voor Urologie / Uitgave 5/2014
Print ISSN: 2211-3037
Elektronisch ISSN: 2211-4718
DOI
https://doi.org/10.1007/s13629-014-0065-9