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Netherlands Heart Journal
Gepubliceerd in:

01-09-2010 | Review article

‘Ins’ and ‘outs’ of triple therapy

Optimal antiplatelet therapy in patients on chronic oral anticoagulation who need coronary stenting

Auteurs: W. Dewilde, N. Breet, J. J. Koolen, J. M. Ten Berg

Gepubliceerd in: Netherlands Heart Journal | Uitgave 9/2010

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Extract

Chronic oral anticoagulant treatment is necessary in patients with mechanical heart valves and in patients with atrial fibrillation and CHADS 2 score >1, with deep venous thrombosis and pulmonary embolism.1,2 Many of these patients also have ischaemic heart disease. When these patients have to undergo percutaneous coronary intervention (PCI) with stenting, there is also an indication for treatment with aspirin and clopidogrel.3 The number of these patients keeps on increasing due to a population that is getting older while life expectancy is increasing. However, triple therapy is known to increase the risk of bleeding complications.1,4,5 We also know that dual antiplatelet treatment and oral anticoagulant treatment are each associated with a nearly 15% risk of major or minor bleeding per year.6 It is still unknown what the best antithrombotic treatment is, when considering both thrombotic (e.g. stent thrombosis) and bleeding complications. Unfortunately, no prospective (randomised) data are available to solve this issue. …
vorige artikel Percutaneous mitral valve repair using the edge-to-edge technique in a high-risk population
volgende artikel Would SYNTAX have been a positive trial if XIENCE V had been used instead of TAXUS?
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Metagegevens
Titel
‘Ins’ and ‘outs’ of triple therapy
Optimal antiplatelet therapy in patients on chronic oral anticoagulation who need coronary stenting
Auteurs
W. Dewilde
N. Breet
J. J. Koolen
J. M. Ten Berg
Publicatiedatum
01-09-2010
Uitgeverij
Bohn Stafleu van Loghum
Gepubliceerd in
Netherlands Heart Journal / Uitgave 9/2010
Print ISSN: 1568-5888
Elektronisch ISSN: 1876-6250
DOI
https://doi.org/10.1007/BF03091812

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