The postpartum period involves several psychological and emotional challenges for parents that can interfere with the quality of parent-infant interactions, which may have negative consequences for the child development and parental mental health. Mindfulness- and compassion-based parenting interventions may help parents develop adaptive parenting skills and adjust better to the parental role during this period, since mindfulness and compassion are considered modifiable and protective skills that allow parents to better regulate their emotions in parenting and to establish a secure relationship with the infant. We conducted a systematic review, according to the PRISMA guidelines, to comprehensively examine the evidence regarding the effect of those interventions applied to the postpartum period. A systematic search of all papers published prior to December 2019 was conducted in four electronic databases. Empirical studies published in peer-reviewed journals with postpartum parents who participated in a mindfulness- and compassion-based intervention were included. After screening 1651 references, we identified nine eligible studies in nine journal articles. The intervention programs were mainly mindfulness-based, with 8 to 12 weekly sessions delivered in a group format. Most of them were conducted with samples of mother-infant dyads, and the baby was present in some or all intervention sessions. The interventions mainly used mindfulness-based formal and informal meditations, interactive play and group discussion and were associated with the promotion of parenting skills and the quality of parental caregiving. Although there is insufficient evidence about the efficacy and effectiveness of the interventions, this systematic review suggests that there are several mindfulness- and compassion-based parenting interventions using different therapeutic techniques that seem to be beneficial for promoting positive parenting skills and the quality of parent-infant relationships in the early parenting years, including the postpartum period.