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Quality of Life Research
Gepubliceerd in:

01-08-2010 | Brief Communication

Quality-of-life measures in Taiwanese adults with symptomatic gallstone disease

Auteurs: Hen-Hui Lien, Chi-Cheng Huang, Pa-Chun Wang, Ching-Shui Huang, Ya-Hui Chen, Tzung-Li Lin, Meng-Chao Tsai

Gepubliceerd in: Quality of Life Research | Uitgave 6/2010

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Abstract

Purpose

The objective of this study was to investigate the association of quality-of-life status with baseline laboratory findings among Taiwanese adults having symptomatic gallstone disease.

Methods

A prospective quality-of-life survey was administered at a tertiary referral medical center among 102 consecutive adults with symptomatic gallstone disease. Patients underwent regular laboratory testing at admission and were evaluated using the 36-Item Short-Form Health Survey (SF-36) and the Gastrointestinal Quality of Life Index (GIQLI). Correlation and regression models were used to investigate quality-of-life predictors.

Results

Compared with the general Taiwanese adult population, patients having symptomatic gallstone disease had significantly poorer performance on all eight SF-36 subscales (P < 0.001). Total GIQLI showed moderate to strong correlation with all eight SF-36 subscale scores (γ = 0.29 ~ 0.62, P < 0.05). In multivariate analysis, serum levels of direct bilirubin (β = −32.6, P = 0.001) and alkaline phosphatase (β = −13.6, P = 0.032) were predictive of worse total GIQLI (adjusted R 2 = 0.183).

Conclusions

Symptomatic gallstone disease may considerably affect patient quality of life in terms of general health status and gastrointestinal-specific measures. Before gallstone surgery, serum levels of direct bilirubin and alkaline phosphatase significantly correlated with quality-of-life measures and can be used to evaluate patient well-being at admission.
volgende artikel Health-related quality of life of “left-behind children”: a cross-sectional survey in rural China
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Metagegevens
Titel
Quality-of-life measures in Taiwanese adults with symptomatic gallstone disease
Auteurs
Hen-Hui Lien
Chi-Cheng Huang
Pa-Chun Wang
Ching-Shui Huang
Ya-Hui Chen
Tzung-Li Lin
Meng-Chao Tsai
Publicatiedatum
01-08-2010
Uitgeverij
Springer Netherlands
Gepubliceerd in
Quality of Life Research / Uitgave 6/2010
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-010-9635-3

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