Top

Gepubliceerd in:

22-02-2022

The health-related quality of life in hyperhidrosis and co-morbidities

Auteurs: Mattias A. S. Henning, Kristina S. Ibler, Isabella Loft, Sisse R. Ostrowski, Christian Erikstrup, Kaspar R. Nielsen, Mie T. Bruun, Henrik Ullum, Maria Didriksen, Khoa M. Dinh, Ole B. Pedersen, Gregor B. E. Jemec

Gepubliceerd in: Quality of Life Research | Uitgave 8/2022

Abstract

Purpose

Hyperhidrosis has been associated with a reduced health-related quality of life (HRQoL). The role of common confounding factors of this association such as stress and socioeconomic status, however, remain largely unexplored, and may affect the management strategy for hyperhidrosis. Therefore, the study objective was to compare the HRQoL in individuals with and without hyperhidrosis while adjusting for confounders.

Methods

In this retrospective cohort study, data on the HRQoL measured by the short-form-12 questionnaire and self-reported hyperhidrosis were collected from the Danish Blood Donor Study-cohort. Data on international classification of disease-10 codes and redeemed prescriptions were collected from nationwide registries. Linear regression investigated the association between hyperhidrosis and HRQoL.

Results

Total 2794 (9.1%) of 30,808 blood donors had self-reported hyperhidrosis and 284 (0.2%) of 122,225 had hospital diagnosed hyperhidrosis. Self-reported hyperhidrosis was associated with a reduced mental HRQoL (adjusted beta coefficient − 1.10; 95% confidence interval − 1.37, − 0.82; p < 0.001) and physical HRQoL (adjusted beta coefficient − 0.90; 95% confidence interval − 1.09, − 0.70; p < 0.001). Hospital diagnosed hyperhidrosis was associated with a reduced mental HRQoL (adjusted beta coefficient − 0.91; 95% confidence interval − 1.82, − 0.04; p = 0.049).

Conclusion

Hyperhidrosis is associated with a reduced HRQoL, independently of confounders or mode of diagnosis. This supports an approach primarily targeting hyperhidrosis.

vorige artikel Health-related quality of life of individuals sharing a household with persons with dementia

volgende artikel A PRO-cision medicine intervention to personalize cancer care using patient-reported outcomes: intervention development and feasibility-testing

Alleen toegankelijk voor geautoriseerde gebruikers

Li, X., Chen, R., Tu, Y. R., Lin, M., Lai, F. C., Li, Y. P., et al. (2007). Epidemiological survey of primary palmar hyperhidrosis in adolescents. Chinese Medical Journal, 120(24), 2215–2217.CrossRef

Tu, Y. R., Li, X., Lin, M., Lai, F. C., Li, Y. P., Chen, J. F., et al. (2007). Epidemiological survey of primary palmar hyperhidrosis in adolescent in Fuzhou of People’s Republic of China. European Journal of Cardio-Thoracic Surgery, 31(4), 737–739. https://doi.org/10.1016/j.ejcts.2007.01.020CrossRefPubMed

Hornberger, J., Grimes, K., Naumann, M., Glaser, D. A., Lowe, N. J., Naver, H., et al. (2004). Recognition, diagnosis, and treatment of primary focal hyperhidrosis. Journal of the American Academy of Dermatology, 51(2), 274–286. https://doi.org/10.1016/j.jaad.2003.12.029CrossRefPubMed

Shayesteh, A., Janlert, U., Brulin, C., Boman, J., & Nylander, E. (2016). Prevalence and characteristics of hyperhidrosis in Sweden: A cross-sectional study in the general population. Dermatology, 232(5), 586–591. https://doi.org/10.1159/000448032CrossRefPubMed

Shayesteh, A., Janlert, U., & Nylander, E. (2017). Hyperhidrosis—Sweating sites matter: Quality of life in primary hyperhidrosis according to the sweating sites measured by SF-36. Dermatology, 233(6), 441–445. https://doi.org/10.1159/000486713CrossRefPubMed

Tetteh, H. A., Groth, S. S., Kast, T., Whitson, B. A., Radosevich, D. M., Klopp, A. C., et al. (2009). Primary palmoplantar hyperhidrosis and thoracoscopic sympathectomy: A new objective assessment method. The Annals of Thoracic Surgery, 87(1), 267–274. https://doi.org/10.1016/j.athoracsur.2008.10.028CrossRefPubMed

Kjeldstrup Kristensen, J., Grejsen, D., Swartling, C., & Bygum, A. (2020). In hyperhidrosis quality of life is even worse than in acne, eczema, or psoriasis. A comparison of Skindex-16 and dermatology life quality index (DLQI). International Journal of Dermatology. https://doi.org/10.1111/ijd.15164CrossRefPubMed

Deckers, I. E., & Kimball, A. B. (2016). The handicap of hidradenitis suppurativa. Dermatologic Clinics, 34(1), 17–22. https://doi.org/10.1016/j.det.2015.07.003CrossRefPubMed

Gross, K. M., Schote, A. B., Schneider, K. K., Schulz, A., & Meyer, J. (2014). Elevated social stress levels and depressive symptoms in primary hyperhidrosis. PLoS ONE, 9(3), e92412. https://doi.org/10.1371/journal.pone.0092412CrossRefPubMedPubMedCentral

10.

Kolotkin, R. L., Meter, K., & Williams, G. R. (2001). Quality of life and obesity. Obesity Reviews, 2(4), 219–229. https://doi.org/10.1046/j.1467-789x.2001.00040.xCrossRefPubMed

11.

Henning, M. A. S., Ibler, K. S., Loft, I., Ullum, H., Erikstrup, C., Nielsen, K. R., et al. (2021). Epidemiology of hyperhidrosis in danish blood donors. Acta Dermato-venereologica. https://doi.org/10.2340/00015555-3790CrossRefPubMed

12.

Goldenberg, M., Danovitch, I., & IsHak, W. W. (2014). Quality of life and smoking. The American Journal on Addictions, 23(6), 540–562. https://doi.org/10.1111/j.1521-0391.2014.12148.xCrossRefPubMed

13.

Brenes, G. A. (2007). Anxiety, depression, and quality of life in primary care patients. Primary Care Companion Journal of Clinical Psychiatry, 9(6), 437–443. https://doi.org/10.4088/pcc.v09n0606CrossRef

14.

Lu, Y. K., Qiao, Y. M., Liang, X., Yao, W., Yan, Z., Wang, H. X., et al. (2019). Reciprocal relationship between psychosocial work stress and quality of life: The role of gender and education from the longitudinal study of the Survey of Health, Ageing and Retirement in Europe. British Medical Journal Open, 9(6), e027051. https://doi.org/10.1136/bmjopen-2018-027051CrossRef

15.

Park, B., Ock, M., Lee, H. A., Lee, S., Han, H., Jo, M. W., et al. (2018). Multimorbidity and health-related quality of life in Koreans aged 50 or older using KNHANES 2013–2014. Health and Quality of Life Outcomes, 16(1), 186. https://doi.org/10.1186/s12955-018-1016-6CrossRefPubMedPubMedCentral

16.

Burgdorf, K. S., Felsted, N., Mikkelsen, S., Nielsen, M. H., Thørner, L. W., Pedersen, O. B., et al. (2016). Digital questionnaire platform in the Danish Blood Donor Study. Computer Methods and Programs in Biomedicine, 135, 101–104. https://doi.org/10.1016/j.cmpb.2016.07.023CrossRefPubMed

17.

Dalgard, F., Svensson, A., Holm, J., & Sundby, J. (2003). Self-reported skin complaints: Validation of a questionnaire for population surveys. The British Journal of Dermatology, 149(4), 794–800. https://doi.org/10.1046/j.1365-2133.2003.05596.xCrossRefPubMed

18.

Ware, J., Kosinski, M. & Keller, S. (1998). SF-12: How to score the SF-12 physical and mental health summary scales.

19.

Christensen, L. N., Ehlers, L., Larsen, F. B., & Jensen, M. B. (2013). Validation of the 12 item short form health survey in a sample from region Central Jutland. Social Indicators Research, 114(2), 513–521. https://doi.org/10.1007/s11205-012-0159-9CrossRef

20.

Gandek, B., Ware, J. E., Aaronson, N. K., Apolone, G., Bjorner, J. B., Brazier, J. E., et al. (1998). Cross-validation of item selection and scoring for the SF-12 Health Survey in nine countries: Results from the IQOLA Project International Quality of Life Assessment. Journal of Clinical Epidemiology, 51(11), 1171–1178.CrossRef

21.

Cohen, S., Kamarck, T., & Mermelstein, R. (1983). A global measure of perceived stress. Journal of Health and Social Behavior, 24(4), 385–396.CrossRef

22.

Eskildsen, A., Dalgaard, V. L., Nielsen, K. J., Andersen, J. H., Zachariae, R., Olsen, L. R., et al. (2015). Cross-cultural adaptation and validation of the Danish consensus version of the 10-item Perceived Stress Scale. Scandinavian Journal of Work, Environment & Health, 41(5), 486–490. https://doi.org/10.5271/sjweh.3510CrossRef

23.

Pedersen, C. G., Davidsen, M., Johansen, N. B., Christensen, A. I., & Tolstrup, J. S. (2017). Sundhedsadfærd og helbred blandt patienter med kontakt til hospital og almen praksis. Syddansk Universitet, Statens Institut for Folkesundhed.

24.

Jia, H., & Lubetkin, E. I. (2009). Time trends and seasonal patterns of health-related quality of life among US adults. Public Health Reports, 124(5), 692–701. https://doi.org/10.1177/003335490912400511CrossRefPubMedPubMedCentral

25.

Claus Zachariae, L. H., Ammitzbøll, E., Secher, L., Thorlacius, L., Bygum, A. & Pallesen, K. (2018). Klinisk vejledning for udredning og behandling af hyperhidrose.

26.

VanderWeele, T. J., & Ding, P. (2017). Sensitivity analysis in observational research: Introducing the E-value. Annals of Internal Medicine, 167(4), 268–274. https://doi.org/10.7326/m16-2607CrossRefPubMed

27.

R Core Team. (2019). R: A Language and Environment for Statistical Computing. R Foundation for Statistical Computing.

28.

Wickham, H. & Miller, E. (2019). haven:Import and Export ’SPSS’, ’Stata’ and ’SAS’ Files.

29.

Hadley Wickham, M. A., et al. (2019). Welcome to the {tidyverse}. Journal of Open Source Software, 4(43), 1686. https://doi.org/10.21105/joss.01686CrossRef

30.

Hamm, H., Naumann, M. K., Kowalski, J. W., Kutt, S., Kozma, C., & Teale, C. (2006). Primary focal hyperhidrosis: Disease characteristics and functional impairment. Dermatology, 212(4), 343–353. https://doi.org/10.1159/000092285CrossRefPubMed

31.

Shayesteh, A., Boman, J., Janlert, U., Brulin, C., & Nylander, E. (2016). Primary hyperhidrosis: Implications on symptoms, daily life, health and alcohol consumption when treated with botulinum toxin. The Journal of Dermatology, 43(8), 928–933. https://doi.org/10.1111/1346-8138.13291CrossRefPubMed

32.

Both, H., Essink-Bot, M. L., Busschbach, J., & Nijsten, T. (2007). Critical review of generic and dermatology-specific health-related quality of life instruments. The Journal of Investigative Dermatology, 127(12), 2726–2739. https://doi.org/10.1038/sj.jid.5701142CrossRefPubMed

33.

Lessa Lda, R., Luz, F. B., De Rezende, R. M., Duraes, S. M., Harrison, B. J., De Menezes, G. B., et al. (2014). The psychiatric facet of hyperhidrosis: Demographics, disability, quality of life, and associated psychopathology. Journal of Psychiatric Practice, 20(4), 316–323. https://doi.org/10.1097/01.pra.0000452570.69578.31CrossRefPubMed

34.

Esmann, S., & Jemec, G. B. (2016). Assessing the quality of life over longer periods. Journal of the European Academy of Dermatology and Venereology, 30(1), 189–190. https://doi.org/10.1111/jdv.12700CrossRefPubMed

35.

Atsma, F., Veldhuizen, I., Verbeek, A., de Kort, W., & de Vegt, F. (2011). Healthy donor effect: Its magnitude in health research among blood donors. Transfusion, 51(8), 1820–1828. https://doi.org/10.1111/j.1537-2995.2010.03055.xCrossRefPubMed

36.

Rigas, A. S., Skytthe, A., Erikstrup, C., Rostgaard, K., Petersen, M. S., Hjalgrim, H., et al. (2019). The healthy donor effect impacts self-reported physical and mental health—Results from the Danish Blood Donor Study (DBDS). Transfusion Medicine (Oxford, England), 29(Suppl 1), 65–69. https://doi.org/10.1111/tme.12478CrossRef

37.

Turner, R. J., & Lloyd, D. A. (2004). Stress burden and the lifetime incidence of psychiatric disorder inyoung adults: Racial and ethnic contrasts. Archives of General Psychiatry, 61(5), 481–488. https://doi.org/10.1001/archpsyc.61.5.481CrossRefPubMed

38.

Mikkelsen, H. T., Haraldstad, K., Helseth, S., Skarstein, S., Småstuen, M. C., & Rohde, G. (2020). Health-related quality of life is strongly associated with self-efficacy, self-esteem, loneliness, and stress in 14–15-year-old adolescents: A cross-sectional study. Health and Quality of Life Outcomes, 18(1), 352. https://doi.org/10.1186/s12955-020-01585-9CrossRefPubMedPubMedCentral

39.

Fryback, D. G., Dunham, N. C., Palta, M., Hanmer, J., Buechner, J., Cherepanov, D., et al. (2007). US norms for six generic health-related quality-of-life indexes from the National Health Measurement study. Medical Care, 45(12), 1162–1170. https://doi.org/10.1097/MLR.0b013e31814848f1CrossRefPubMedPubMedCentral

40.

Espelt, A., Font-Ribera, L., Rodriguez-Sanz, M., Artazcoz, L., Ferrando, J., Plaza, A., et al. (2010). Disability among older people in a southern European city in 2006: Trends in gender and socioeconomic inequalities. Journal of Women’s Health, 19(5), 927–933. https://doi.org/10.1089/jwh.2009.1608CrossRefPubMed

41.

Murtagh, K. N., & Hubert, H. B. (2004). Gender differences in physical disability among an elderly cohort. American Journal of Public Health, 94(8), 1406–1411. https://doi.org/10.2105/ajph.94.8.1406CrossRefPubMedPubMedCentral

42.

Zhao, Y., Zhou, Z., Fan, X., Nawaz, R., Zhao, D., Xu, T., et al. (2021). Comparison of inequity in health-related quality of life among unemployed and employed individuals in China. BMC Public Health, 21(1), 52. https://doi.org/10.1186/s12889-020-10038-3CrossRefPubMedPubMedCentral

43.

Kamudoni, P., Mueller, B., Halford, J., Schouveller, A., Stacey, B., & Salek, M. S. (2017). The impact of hyperhidrosis on patients’ daily life and quality of life: A qualitative investigation. Health and Quality of Life Outcomes, 15(1), 121. https://doi.org/10.1186/s12955-017-0693-xCrossRefPubMedPubMedCentral

44.

Solish, N., Wang, R., & Murray, C. A. (2008). Evaluating the patient presenting with hyperhidrosis. Thoracic Surgery Clinics, 18(2), 133–140. https://doi.org/10.1016/j.thorsurg.2008.01.002CrossRefPubMed

Titel: The health-related quality of life in hyperhidrosis and co-morbidities
Auteurs: Mattias A. S. Henning
Kristina S. Ibler
Isabella Loft
Sisse R. Ostrowski
Christian Erikstrup
Kaspar R. Nielsen
Mie T. Bruun
Henrik Ullum
Maria Didriksen
Khoa M. Dinh
Ole B. Pedersen
Gregor B. E. Jemec
Publicatiedatum: 22-02-2022
Uitgeverij: Springer International Publishing
Gepubliceerd in: Quality of Life Research / Uitgave 8/2022
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI: https://doi.org/10.1007/s11136-022-03108-z

Andere artikelen Uitgave 8/2022

A PRO-cision medicine intervention to personalize cancer care using patient-reported outcomes: intervention development and feasibility-testing

Quality of life profiles and their association with clinical and demographic characteristics and physical activity in people with a stoma: a latent profile analysis

Open Access

Clinical utility of PTSD, resilience, sleep, and blast as risk factors to predict poor neurobehavioral functioning following traumatic brain injury: A longitudinal study in U.S. military service members

Impact of postanesthesia care unit delirium on self-reported cognitive function and perceived health status: a prospective observational cohort study

Open Access

Health-related quality of life in cancer immunotherapy: a systematic perspective, using causal loop diagrams

Open Access

Flattening the quality of life curve? A prospective person-centred study from Norway amid COVID-19

Open Access

Bohn Stafleu van Loghum

Welkom bij Scalda & Bohn Stafleu van Loghum

Registreer

Login

The health-related quality of life in hyperhidrosis and co-morbidities

Abstract

Purpose

Methods

Results

Conclusion

Andere artikelen Uitgave 8/2022

A PRO-cision medicine intervention to personalize cancer care using patient-reported outcomes: intervention development and feasibility-testing

Quality of life profiles and their association with clinical and demographic characteristics and physical activity in people with a stoma: a latent profile analysis

Clinical utility of PTSD, resilience, sleep, and blast as risk factors to predict poor neurobehavioral functioning following traumatic brain injury: A longitudinal study in U.S. military service members

Impact of postanesthesia care unit delirium on self-reported cognitive function and perceived health status: a prospective observational cohort study

Health-related quality of life in cancer immunotherapy: a systematic perspective, using causal loop diagrams

Flattening the quality of life curve? A prospective person-centred study from Norway amid COVID-19

Bohn Stafleu van Loghum

Welkom bij Scalda & Bohn Stafleu van Loghum

Registreer

Login

Deel dit onderdeel of sectie (kopieer de link)

Abstract

Purpose

Methods

Results

Conclusion

Log in om toegang te krijgen

A PRO-cision medicine intervention to personalize cancer care using patient-reported outcomes: intervention development and feasibility-testing

Quality of life profiles and their association with clinical and demographic characteristics and physical activity in people with a stoma: a latent profile analysis

Clinical utility of PTSD, resilience, sleep, and blast as risk factors to predict poor neurobehavioral functioning following traumatic brain injury: A longitudinal study in U.S. military service members

Impact of postanesthesia care unit delirium on self-reported cognitive function and perceived health status: a prospective observational cohort study

Health-related quality of life in cancer immunotherapy: a systematic perspective, using causal loop diagrams

Flattening the quality of life curve? A prospective person-centred study from Norway amid COVID-19