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2014 | OriginalPaper | Hoofdstuk
16. Non-hodgkinlymfoom
Auteurs : Fazil Baboe, Elly Lugtenburg
Gepubliceerd in: Ontwikkelingen in de oncologie
Uitgeverij: Bohn Stafleu van Loghum
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Inleiding
Het non-hodgkinlymfoom (NHL) is een verzamelnaam voor ongeveer vijftig verschillende klinisch-pathologische entiteiten die zijn omschreven in de WHO-classificatie van 2008.1 NHL is een zeldzame ziekte, met in westerse landen een incidentie van 10-15 per 100.000 in de algemene bevolking. De huisarts zal elke 3 jaar gemiddeld één nieuwe patiënt tegenkomen. De incidentie neemt toe met de leeftijd: 60% van de patiënten is ten tijde van de diagnose ouder dan 60 jaar. In 90% van de gevallen ontstaat NHL in een ontspoorde B-lymfocyt, slechts 10% ontstaat in een T-cel. In dit hoofdstuk bespreken wij de twee vaakst voorkomende subtypes: het folliculair non-hodgkinlymfoom (FL
), dat tamelijk indolent is en 20-30% van alle NHL uitmaakt, en het diffuus grootcellig B-cellymfoom (DLBCL
), dat agressief is en 40% van alle NHL uitmaakt.
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Metagegevens
- Titel
- Non-hodgkinlymfoom
- Auteurs
-
Fazil Baboe
Elly Lugtenburg
- Copyright
- 2014
- Uitgeverij
- Bohn Stafleu van Loghum
- Boek
-
Ontwikkelingen in de oncologie
Print ISBN: 978-90-368-0435-6
Elektronisch ISBN: 978-90-368-0436-3
Copyright: 2014
- DOI
- https://doi.org/10.1007/978-90-368-0436-3_16