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29-10-2024

Quality of life of inflammatory bowel diseases patients in france with EQ-5D-5 L: the QALY-MICI study

Auteurs: H. Sarter, J. Kirschgesner, L. Beaugerie, A. Buisson, C. Gower-Rousseau, Gérard de Pouvourville

Gepubliceerd in: Quality of Life Research | Uitgave 2/2025

Abstract

Purpose

This study aimed to document utility values and the Visual Analog Scale (VAS) with the 5-level version of the EQ-5D questionnaire in a large sample of patients with inflammatory bowel disease (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC).

Methods

QALY-MICI was a cross-sectional survey across three sources in France. Data were collected between 2019 and 2022 for patients 18 and over. The EQ-5D-5 L, the EQ-VAS, the Short Inflammatory Bowel Disease Questionnaire (SIBDQ), the Harvey-Bradshaw Index (HBI) for CD, and the Walmsley Index for UC (SCCAI) were collected.

Results

A total of 2,841 patients aged over 18 were recruited (1785 with CD, 1056 with UC). The mean age was 40.2 (SD 14.3). The time since diagnosis was 6 years and over for 61.9% of patients. The most impacted dimensions were usual activities, anxiety/ depression, and pain/ discomfort. The mean utility value was 0.863 (SD 0.172) versus 0.905 (SD 0.158) in the French population (p = 0.007). The mean VAS value was 68 (SD 19.2) versus 73.4 (SD 22.2) in the general population (p = 0.016). Utility values and VAS were similar for CD and UC and higher for men. There was a strong positive correlation between utility values, the VAS, and the SIBDQ score, and a negative correlation between the HBI and the SCCAI. The SIBDQ score and disease activity were the main predictors of utility and VAS.

Conclusion

The QALY-MICI is, to our knowledge, the first study documenting utility values and VAS using the EQ-5D-5 L questionnaire on a large sample, with a comparison to the general population.

vorige artikel Testing the psychometric characteristics of EQ-5D-5L and respiratory bolt-ons using a sample of the Australian population

volgende artikel EQ-5D-5L value set for Norway: a hybrid model using cTTO and DCE data

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Titel: Quality of life of inflammatory bowel diseases patients in france with EQ-5D-5 L: the QALY-MICI study
Auteurs: H. Sarter
J. Kirschgesner
L. Beaugerie
A. Buisson
C. Gower-Rousseau
Gérard de Pouvourville
Publicatiedatum: 29-10-2024
Uitgeverij: Springer New York
Gepubliceerd in: Quality of Life Research / Uitgave 2/2025
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI: https://doi.org/10.1007/s11136-024-03821-x

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Quality of life of inflammatory bowel diseases patients in france with EQ-5D-5 L: the QALY-MICI study

Abstract

Purpose

Methods

Results

Conclusion

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Abstract

Purpose

Methods

Results

Conclusion

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