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Gepubliceerd in:

13-09-2024

The association of the comorbidity status of metabolic syndrome and cognitive dysfunction with health-related quality of life

Auteurs: Yi-Hsuan Lin, Hsiao-Ting Chang, Yen-Feng Wang, Jong-Ling Fuh, Shuu-Jiun Wang, Harn-Shen Chen, Sih-Rong Li, Ming-Hwai Lin, Tzeng-Ji Chen, Shinn-Jang Hwang

Gepubliceerd in: Quality of Life Research | Uitgave 12/2024

Abstract

Purpose

Both metabolic syndrome (MetS) and cognitive dysfunction impair health-related quality of life (HRQOL). This study aims to determine whether individuals experiencing both MetS and cognitive dysfunction have lower HRQOL.

Methods

This cross-sectional study enrolled 567 participants who attended outpatient clinics at a medical center in northern Taiwan. MetS was diagnosed according to the modified criteria for the Asian population. Cognitive function was categorized as normal, mild cognitive dysfunction, and advanced cognitive dysfunction according to the score of the Montreal Cognitive Assessment, Taiwanese version. HRQOL was assessed using the SF-36v2® Health Survey (SF-36v2). The associations of the comorbidity status of MetS and cognitive dysfunction with HRQOL were analyzed using linear regression models, adjusting for age, sex, marital status, education level, income groups, and activities of daily living.

Results

Out of 567 participants, 33 (5.8%) had MetS with mild cognitive dysfunction, and 34 (6.0%) had MetS with advanced cognitive dysfunction. Participants with both MetS and advanced cognitive dysfunction exhibited the lowest scores in the physical component summary and almost all scales of HRQOL. MetS exacerbated the inverse association between mild cognitive dysfunction and the mental component summary. For those with MetS, the scores on scales of role physical, bodily pain, vitality, and social functioning worsened as cognitive function deteriorated (all P_trend<0.05).

Conclusion

As the severity of comorbidity between MetS and cognitive dysfunction varies, patients exhibited poorer performance in different aspects of HRQOL. Future research is needed to find solutions to improve HRQOL for patients with both MetS and cognitive dysfunction.

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Titel: The association of the comorbidity status of metabolic syndrome and cognitive dysfunction with health-related quality of life
Auteurs: Yi-Hsuan Lin
Hsiao-Ting Chang
Yen-Feng Wang
Jong-Ling Fuh
Shuu-Jiun Wang
Harn-Shen Chen
Sih-Rong Li
Ming-Hwai Lin
Tzeng-Ji Chen
Shinn-Jang Hwang
Publicatiedatum: 13-09-2024
Uitgeverij: Springer International Publishing
Gepubliceerd in: Quality of Life Research / Uitgave 12/2024
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI: https://doi.org/10.1007/s11136-024-03784-z

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The association of the comorbidity status of metabolic syndrome and cognitive dysfunction with health-related quality of life

Abstract

Purpose

Methods

Results

Conclusion

Andere artikelen Uitgave 12/2024

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Welkom bij Scalda & Bohn Stafleu van Loghum

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Abstract

Purpose

Methods

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Conclusion

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